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Krawczyk et al., J Immunol 2008
:
Conversely, Jagged1 expression is markedly induced by TLR ligation
Foldi et al., J Immunol 2010
:
Autoamplification of Notch signaling in macrophages by TLR induced and RBP-J dependent induction of Jagged1 ... Strikingly, TLR induced Jagged1 expression was strongly dependent on the Notch master transcriptional regulator RBP-J and also on upstream components of the Notch pathway ?-secretase and Notch1 and Notch2 receptors