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HSP90AA1 — JAK1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: JAK1 — HSP90AA1 (physical association, affinity chromatography technology) Taipale et al., Cell 2012
• IRef Intact Interaction: Complex of 76 proteins (association, anti tag coimmunoprecipitation) Weinmann et al., Cell 2009

Text-mined interactions from Literome

Plo et al., Blood 2008 (Myeloproliferative Disorders...) : Moreover, JAK2 activation increased centrosome and ploidy abnormalities
Schoof et al., Cell communication and signaling : CCS 2009 : HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells
Weigert et al., J Exp Med 2012 (Leukemia, B-Cell...) : Thus, HSP90 is a promising therapeutic target in JAK2-driven cancers, including those with genetic resistance to JAK enzymatic inhibitors