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AGTR1 — JUN

Text-mined interactions from Literome

Wu et al., Free Radic Biol Med 2005 : Together, these findings indicate that Ang-II elicits the activation of the redox-sensitive AP-1 via ROS through AT1 , resulting in effects on cardiomyocyte function such as hypertrophy
Liu et al., Circ Res 2006 (Body Weight...) : Neuronal angiotensin II type 1 receptor upregulation in heart failure : activation of activator protein 1 and Jun N-terminal kinase
Zucker et al., Am J Physiol Heart Circ Physiol 2009 (Chronic Disease...) : There is now good evidence that AT(1)R expression in neurons is mediated by activation of the transcription factor activator protein 1 (AP-1)
Wang et al., Zhonghua Shao Shang Za Zhi 2010 (Acute Lung Injury) : [ Role of angiotensin II type 1 receptor in activation of nuclear factor-kappaB and activator protein-1 in lung of mice with acute lung injury ] ... To explore the role of angiotensin II type 1 (AT1) receptor in activation of nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) in lung of mice with LPS induced acute lung injury ( ALI )
Wang et al., Experimental biology and medicine (Maywood, N.J.) 2012 (Inflammation) : Forced over-expression of AT1R resulted in activation of MAPKs, c-Jun and NF-?B, up-regulation of inflammatory genes and LOX-1 ; on the other hand forced AT2R over-expression induced up-regulation of pro-apoptotic signals ( pro-IL-1ß and IL-1ß ), and decreased LOX-1 expression