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INS — KCNMA1
Text-mined interactions from Literome
O'Malley et al., Mol Pharmacol 2004
:
Furthermore,
insulin activation of this pathway
enhances BK channel activity by shifting the Ca ( 2+ ) -sensitivity such that BK channels are active at more hyperpolarized membrane potentials
O'Malley et al., Eur J Neurosci 2007
(Epilepsy...) :
MAPK dependent actin cytoskeletal reorganization underlies
BK channel activation by
insulin ... Here we demonstrate that in hippocampal neurons,
BK channel activation by
insulin is blocked by actin filament stabilization, suggesting that this process is dependent on the actin cytoskeleton ... These data are consistent with
BK channel activation by
insulin involving MAPK dependent alterations in actin dynamics