We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to INS

INS — KCNMA1

Text-mined interactions from Literome

O'Malley et al., Mol Pharmacol 2004 : Furthermore, insulin activation of this pathway enhances BK channel activity by shifting the Ca ( 2+ ) -sensitivity such that BK channels are active at more hyperpolarized membrane potentials
O'Malley et al., Eur J Neurosci 2007 (Epilepsy...) : MAPK dependent actin cytoskeletal reorganization underlies BK channel activation by insulin ... Here we demonstrate that in hippocampal neurons, BK channel activation by insulin is blocked by actin filament stabilization, suggesting that this process is dependent on the actin cytoskeleton ... These data are consistent with BK channel activation by insulin involving MAPK dependent alterations in actin dynamics