Gene interactions and pathways from curated databases and text-mining

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IL2 — KIR2DL1

Text-mined interactions from Literome

Kogure et al., Mediators Inflamm 1999 : These findings suggest that IL-2 plays an important role in the regulation of CD158a/b expression, and might be involved in controlling NK activity via regulating expression of these molecules
Pan et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003 : IL-2 plays an important role in the regulation of CD158a/b expression or proliferation of CD158a+/b+ cells
Chrul et al., Mediators Inflamm 2006 : In the present study, we analyze the modulatory effect of IL-2 alone or a combination of IL-12 with IL-18 on surface expression of killer cell immunoglobulin-like receptors KIR2DL1 , KIR2DL2, and KIR3DL2 in NK cells
Hromadnikova et al., Mediators Inflamm 2013 : Using flow cytometry the effect of in vitro stimulation with IL-2 or IL-15 alone or in combination with Hsp70 derived 14-mer peptide ( TKD ) on cell surface expression of NK activatory receptors ( CD16, NKG2D, NKG2C, NKp46, NKp44, NKp30, KIR2DL4 , DNAM-1, and LAMP1 ) and NK inhibitory receptors ( NKG2A, KIR2DL2/L3, LIR1/ILT-2, and NKR-P1A ) in healthy individuals was studied