Gene interactions and pathways from curated databases and text-mining

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KLF2 — NOS2

Text-mined interactions from Literome

SenBanerjee et al., J Exp Med 2004 (Inflammation) : Overexpression of KLF2 in umbilical vein endothelial cells robustly induced endothelial nitric oxide synthase expression and total enzymatic activity
Huddleson et al., J Biol Chem 2005 : Finally, we have found that KLF2 increases endothelial nitric-oxide synthase expression in murine endothelial cultures, an effect that is also blocked by PI3K inhibition
Ali et al., J Biol Chem 2009 : Mechanistically, synergy required Akt phosphorylation, activation of Kruppel-like factor 2 , NF-E2 related factor-2 (Nrf2), increased nitric-oxide synthase activity, and enhanced HO-1 mRNA stability
Boon et al., Eur Heart J 2011 (Coronary Artery Disease...) : Lentiviral overexpression of KLF2 increased human PAC numbers and endothelial nitric oxide synthase expression by 60 % during in vitro culture