Gene interactions and pathways from curated databases and text-mining

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AKT2 — KLF4

Text-mined interactions from Literome

Ghosh et al., J Biol Chem 2012 (Neurodegenerative Diseases) : This study delineates a novel property of gemfibrozil in up-regulating SOCS3 in glial cells via PI 3-kinase-AKT mediated activation of KLF4 and suggests that gemfibrozil may find therapeutic application in neuroinflammatory and neurodegenerative disorders
Li et al., Microvasc Res 2012 : Furthermore, overexpression of KLF4 in EPCs enhanced the expression of CD34 and alleviated cell differentiation but did not increase the phosphorylation of Akt