Gene interactions and pathways from curated databases and text-mining

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IFNG — KLRC1

Text-mined interactions from Literome

Tieng et al., Proc Natl Acad Sci U S A 2002 (Crohn Disease) : MICA induction on epithelial cells triggered IFN-gamma release by the NKG2D expressing natural killer cell line NKL
Derre et al., J Immunol 2002 (Melanoma) : We show that IL-12 induces the expression of NKG2-A and/or CD94 by CD8 ( + ) T cells in culture, and that this induction was mediated neither by IFN-gamma nor by IL-15
Koike et al., J Exp Med 2004 : Furthermore, anti-NKG2I mAb inhibited NK cell mediated cytotoxicity, whereas cross linking of NKG2I enhanced interleukin 2- and interleukin 12-dependent interferon-gamma production
Rincon-Orozco et al., J Immunol 2005 : Furthermore, NKG2D triggers the production of TNF-alpha but not of IFN-gamma , as well as the release of cytolytic granules by Vgamma9 Vdelta2 T cells
Ortaldo et al., Blood 2006 : Our studies demonstrate that cross linking of NKG2D and NK1.1 results in a synergistic NK IFN-gamma response when combined with IL-12 or IL-18
Nitahara et al., J Invest Dermatol 2006 : Cross linking of NKG2D on DETCs induced IFN-gamma production
Girart et al., J Immunol 2007 (Melanoma) : Engagement of TLR3, TLR7, and NKG2D regulate IFN-gamma secretion but not NKG2D mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12 ... Excitingly, IFN-gamma secretion was significantly increased when NK cells were stimulated with poly ( I:C ) or loxoribine and IL-12, and NKG2D engagement was induced by coculture with MICA+ tumor cells in a PI3K dependent manner
Vahlne et al., Scand J Immunol 2008 : A comparison of responses in naive mouse NK cells and NK cells pre activated with the type I interferon-inducer tilorone demonstrated a dramatic influence of pre-activation, allowing potent degranulation and IFN-gamma responses to NKG2D mediated stimulation that were not observed with naive NK cells
Wang et al., Mol Immunol 2008 : NKG2D receptor-ligand interaction triggers NK cell mediated cytolysis and IFN-gamma secretion
Hidano et al., Int Immunol 2008 : Although NKG2D mediated IFN-gamma production depends on phospholipase C (PLC) gamma 2, YAC-1 cell triggered IFN-gamma production is PLC gamma 2- and Syk/ZAP-70 independent and nuclear factor-kappa B mediated
Clayton et al., J Immunol 2008 (Mesothelioma...) : Lymphocyte effector function was impaired by pretreatment with tumor exosomes, as these cells exhibited poor NKG2D dependent production of IFN-gamma and poor NKG2D dependent killing function
Schwinn et al., Int J Cancer 2009 (Glioma...) : Here, we asked whether the proinflammatory cytokine Interferon-gamma (IFN-gamma) affects NKG2DL expression in melanoma
Fuertes et al., Medicina (B Aires) 2011 (Nevus...) : Engagement of NKG2D by MICA triggers IFN-g secretion and cytotoxicity against malignant cells