◀ Back to CNTN2
CNTN2 — LCK
Text-mined interactions from Literome
Akagi et al., Blood 1995
(Cell Transformation, Viral) :
These changes in the expression of Lyn,
Lck , and cell-surface CD3 antigen probably
resulted from indirect effects of
Tax1 that appeared after extended culture
Lemasson et al., J Virol 1997
:
By using Jurkat T cells stably transfected with constructs that expressed either the 3 ' end of the HTLV-1 genome ( JK C11-pMTEX ), the tax gene ( JK52-Tax ) or the rex gene ( JK9-Rex ), we found that
the expression of p40tax (Tax) was
sufficient to modulate
p56lck protein expression ... In contrast, cadmium induction of Tax in JPX-9 cells transiently transfected with a CAT construct driven by a lck DP with a deletion extending from position -259 to -253 ( a sequence corresponding to a putative E-Box ) did not modulate CAT gene expression, suggesting that the
effect of
Tax on
p56lck is mediated through an E-Box binding protein