Gene interactions and pathways from curated databases and text-mining

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CNTN2 — LCK

Text-mined interactions from Literome

Akagi et al., Blood 1995 (Cell Transformation, Viral) : These changes in the expression of Lyn, Lck , and cell-surface CD3 antigen probably resulted from indirect effects of Tax1 that appeared after extended culture
Lemasson et al., J Virol 1997 : By using Jurkat T cells stably transfected with constructs that expressed either the 3 ' end of the HTLV-1 genome ( JK C11-pMTEX ), the tax gene ( JK52-Tax ) or the rex gene ( JK9-Rex ), we found that the expression of p40tax (Tax) was sufficient to modulate p56lck protein expression ... In contrast, cadmium induction of Tax in JPX-9 cells transiently transfected with a CAT construct driven by a lck DP with a deletion extending from position -259 to -253 ( a sequence corresponding to a putative E-Box ) did not modulate CAT gene expression, suggesting that the effect of Tax on p56lck is mediated through an E-Box binding protein