◀ Back to CPOX

CPOX — LEO1

Text-mined interactions from Literome

Fabi et al., Br J Pharmacol 2001 : 1. To further investigate into the mechanisms of PAF induced cardiopulmonary actions, we examined the effects of the nitric oxide synthase (NOS) inhibitor L-N ( omega ) -nitro-L-arginine ( L-NNA ), of the specific cyclooxygenase-2 (COX-2) inhibitor NS 398, and of the combined presence of both COX and NOS inhibitors on the PAF responses in the heart lung preparation of guinea-pig ( HLP ) ... Furthermore, an interaction between PAF stimulated COX , particularly COX-2, and NOS pathways appears to take a functional role at both bronchial and cardiovascular level
Shah et al., Exp Mol Med 2001 : These data suggest that synergistic effect of 5-HT and PAF on human platelet aggregation involves activation of PLC/Ca2+, COX and MAP kinase pathways
Walterscheid et al., J Exp Med 2002 : Both UV and PAF activated cyclooxygenase (COX)-2 and IL-10 reporter gene construct transcription
Hidalgo et al., Br J Pharmacol 2005 : 6. Andrographolide reduced cyclooxygenase-2 (COX-2) expression induced by PAF and fMLP in HL-60/neutrophils