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IL12A — LGALS9

Text-mined interactions from Literome

Dai et al., J Immunol 2005 : Gal-9 induced phosphorylation of the MAPK p38 and ERK1/2 in DCs, and an inhibitor of p38 signaling, but not inhibitors of signaling by either ERK1/2 or PI3K, blocked Gal-9 induced up-regulation of costimulatory molecule expression and IL-12 production
Yamauchi et al., Nihon Rinsho Meneki Gakkai Kaishi 2005 : Gal-9 induced phosphorylation of the p38 MAPK and ERK1/2 in DCs, and an inhibitor of p38 signaling, but not inhibitors of signaling by either ERK1/2 or phosphatidylinositol 3-kinase, blocked Gal-9 induced up-regulation of costimulatory molecule expression and IL-12 production
Tsuboi et al., Clin Immunol 2007 (Shwartzman Phenomenon) : The fact that Gal-9 does not suppress LPS induced TNF-alpha, IFN-gamma and IL-12 production in neutropenic mice, and that it does not protect those mice from the Shwartzman reaction, confirms the involvement of PMN in regulation
Ma et al., PloS one 2013 : In this study, our data suggest that Tim-3 and IL-12/IL-23 gene transcriptions are regulated by enhanced or silenced Gal-9 expression within monocytes through synergizing with TLR signaling