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LIF — PIK3R1
Text-mined interactions from Literome
Miyamoto et al., Cell Death Differ 2008
:
HK-II contains consensus sequences for phosphorylation by Akt and
LIF treatment
induces PI3K- and Akt dependent HK-II phosphorylation
Fahmi et al., Cell Signal 2013
(Hypertrophy...) :
Both
LIF and IL-6 [ in the absence of soluble IL-6 receptor ( sIL-6Ra ) ]
activated Erk1/2, JNK1/2, p38-MAPK and
PI3K signalling peaking at 20min and induced cytoprotection against simulated ischemia-reperfusion injury which was blocked by the MEK1/2 inhibitor PD98059 but not the p38-MAPK inhibitor SB203580