Gene interactions and pathways from curated databases and text-mining

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LIF — PIK3R1

Text-mined interactions from Literome

Miyamoto et al., Cell Death Differ 2008 : HK-II contains consensus sequences for phosphorylation by Akt and LIF treatment induces PI3K- and Akt dependent HK-II phosphorylation
Fahmi et al., Cell Signal 2013 (Hypertrophy...) : Both LIF and IL-6 [ in the absence of soluble IL-6 receptor ( sIL-6Ra ) ] activated Erk1/2, JNK1/2, p38-MAPK and PI3K signalling peaking at 20min and induced cytoprotection against simulated ischemia-reperfusion injury which was blocked by the MEK1/2 inhibitor PD98059 but not the p38-MAPK inhibitor SB203580