Gene interactions and pathways from curated databases and text-mining

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LYN — PIK3R1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Qin et al., Biochemistry 2003 : Under our conditions, hydrogen peroxide induced PI3K and Akt activation was independent of Lyn , Syk, Cbl, BCAP, or Ras when each was eliminated individually either by mutation or by a specific inhibitor
Xu et al., Immunol Cell Biol 2012 : Regulating SFK activity may thus be a central mechanism by which Lyn regulates PI3K activity in B cells