Gene interactions and pathways from curated databases and text-mining

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MAP3K5 — PIK3R1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Yang et al., Cell Microbiol 2006 (MAP Kinase Signaling System) : Furthermore, the inhibition of PI3K-Akt , but not ERK 1/2 pathway, attenuated M. tbc induced S6K1 phosphorylation, whereas PI3K inhibition enhanced p38 phosphorylation and apoptosis signal regulating kinase 1 activity during exposure to M. tbc
Autret et al., J Virol 2008 : JNK inhibition is associated with PI3K dependent negative regulation of the apoptosis signal regulating kinase 1 , which acts upstream from JNK in PV-infected IMR5 cells