Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Zheng et al., J Neurosci Res 2009 : Moreover, we found that inhibition of calmodulin (CaM) by W13 blocked both Arc transcription and ERK activation, revealing a Ca ( 2+ ) -independent function of CaM
Kumar et al., J Biol Chem 2012 (Synaptic Transmission) : Mechanistically, intracellular mGluR5 mediated Arc induction is dependent upon extracellular and intracellular Ca ( 2+ ) and ERK1/2 as well as calmodulin dependent kinases as known chelators, inhibitors, and a dominant negative Ca ( 2+ ) /calmodulin dependent protein kinase II construct block Arc increases