Gene interactions and pathways from curated databases and text-mining

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MET — MMP2

Text-mined interactions from Literome

Torres et al., Clin Cancer Res 2011 (Neoplasm Invasiveness...) : MET activation increased MPNST cell motility, invasion, angiogenesis, and induced matrix metalloproteinase-2 (MMP2) and VEGF expression ; MET knockdown had inverse effects in vitro and markedly decreased local and metastatic growth in vivo
Zhang et al., Curr Mol Med 2012 (Breast Neoplasms...) : Addition of sera obtained from patients treated with combination of radiotherapy and EGCG feeding for 2-8 weeks to in vitro cultures of highly-metastatic human MDA-MB-231 breast cancer cells resulted in the following significant changes : ( 1 ) suppression of cell proliferation and invasion ; ( 2 ) arrest of cell cycles at the G0/G1 phase ; ( 3 ) reduction of activation of MMP9/MMP2 , expressions of Bcl-2/Bax, c-Met receptor, NF-?B, and the phosphorylation of Akt
Baek et al., J Immunol 2012 (Inflammation) : Additionally, we found that Met signaling regulates matrix metalloproteinase MMP2 and MMP9 activity, which is important for DC migration through extracellular matrix