Gene interactions and pathways from curated databases and text-mining

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IRF6 — MLYCD

Text-mined interactions from Literome

Tsan et al., Am J Physiol Cell Physiol 2001 : In the current study, we evaluated the role of mCD14 and TLR4 in LPS induction of MnSOD using peritoneal macrophages from CD14 knockout (CD14-KO) mice and mice with the Tlr4 gene point mutation ( C3H/HeJ ) or deletion ( C57BL/10ScCr )
Creery et al., Clin Diagn Lab Immunol 2002 : This enhanced mCD14 expression and sCD14 production in HIV infected individuals may be due to the effects of cytokines, the bacterial product lipopolysaccharide (LPS) , and/or the HIV regulatory antigens Tat and Nef ... Interleukin-10 (IL-10), an immunoregulatory cytokine, as well as LPS enhanced mCD14 expression and the release of sCD14 in the culture supernatants
Tamai et al., J Endotoxin Res 2003 : LPS and IFN-gamma enhanced mCD14 and Toll-like receptor (TLR) 4 expression in THP-1 cells, respectively, and co-stimulation with LPS and IFN-gamma induced higher levels of mCD14 and TLR4 expression than stimulation with either agent alone
Wang et al., Cytokine 2010 : ApoA-I diminished LPS induced mCD14 expression ( P < 0.01 ) and NFkappaB nuclear translocation in THP-1 cells
Landmann et al., Infect Immun 1996 : After 6 to 15 h, LPS weakly reduced CD14 mRNA and mCD14 and transiently enhanced sCD14 release ... In contrast, the LPS induced increases CD14 mRNA, mCD14 , and sCD14 were stronger and appeared earlier after a second LPS challenge
Wang et al., J Biol Chem 1998 : PtdIns binding to mCD14 can be blocked by anti-CD14 monoclonal antibodies that inhibit LPS-mCD14 binding, and PtdIns can inhibit both LPS-mCD14 binding and LPS induced responses in monocytes