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IRF6 — MLYCD
Text-mined interactions from Literome
Tsan et al., Am J Physiol Cell Physiol 2001
:
In the current study, we evaluated the
role of
mCD14 and TLR4 in
LPS induction of MnSOD using peritoneal macrophages from CD14 knockout (CD14-KO) mice and mice with the Tlr4 gene point mutation ( C3H/HeJ ) or deletion ( C57BL/10ScCr )
Creery et al., Clin Diagn Lab Immunol 2002
:
This enhanced
mCD14 expression and sCD14 production in HIV infected individuals may be
due to the effects of cytokines, the bacterial product
lipopolysaccharide (LPS) , and/or the HIV regulatory antigens Tat and Nef ... Interleukin-10 (IL-10), an immunoregulatory cytokine, as well as
LPS enhanced
mCD14 expression and the release of sCD14 in the culture supernatants
Tamai et al., J Endotoxin Res 2003
:
LPS and IFN-gamma enhanced mCD14 and Toll-like receptor (TLR) 4 expression in THP-1 cells, respectively, and co-stimulation with LPS and IFN-gamma
induced higher levels of
mCD14 and TLR4 expression than stimulation with either agent alone
Wang et al., Cytokine 2010
:
ApoA-I diminished
LPS induced
mCD14 expression ( P < 0.01 ) and NFkappaB nuclear translocation in THP-1 cells
Landmann et al., Infect Immun 1996
:
After 6 to 15 h,
LPS weakly
reduced CD14 mRNA and
mCD14 and transiently enhanced sCD14 release ... In contrast, the
LPS induced increases CD14 mRNA,
mCD14 , and sCD14 were stronger and appeared earlier after a second LPS challenge
Wang et al., J Biol Chem 1998
:
PtdIns binding to mCD14 can be blocked by anti-CD14 monoclonal antibodies that inhibit LPS-mCD14 binding, and PtdIns can inhibit both
LPS-mCD14 binding and
LPS induced
responses in monocytes