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Lee et al., J Gene Med 2006
(Inflammation...) :
Further, alpha-MSH significantly increased matrix metalloproteinase ( MMP ) activity with tissue inhibitors of matrix metalloproteinase ( TIMP ) inactivation
Wang et al., Gene Ther 2006
(Fibrosis...) :
Further, alpha-MSH significantly increased matrix metalloproteinase ( MMP ) , while tissue inhibitors of matrix metalloproteinase ( TIMPs ) were inactivated
Yoon et al., Osteoarthritis Cartilage 2008
(Chondrosarcoma) :
The effect of alpha-MSH on TNF-alpha induced MMP-13 expression and mitogen activated protein kinases ' ( MAPKs ) activation were determined by reverse transcriptase-polymerase chain reaction and Western blot analysis