Gene interactions and pathways from curated databases and text-mining

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CPOX — MMP14

Text-mined interactions from Literome

Lara-Pezzi et al., J Clin Invest 2002 (Carcinoma, Hepatocellular...) : Induction of both MT1-MMP expression and cell invasion by HBx is dependent on cyclooxygenase-2 (COX-2) activity
Spinella et al., Cancer Res 2007 (Melanoma...) : Moreover, COX-1/COX-2 inhibitors block ET-induced PGE ( 2 ) and VEGF secretion, matrix metalloproteinase ( MMP ) activation, and cell invasion, indicating that both enzymes function as downstream mediators of ET-induced invasive properties