Gene interactions and pathways from curated databases and text-mining

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MMP14 — TNFSF10

Text-mined interactions from Literome

Zhou et al., Hepatobiliary Pancreat Dis Int 2008 (Pancreatic Neoplasms) : The purpose of this study was to find out if TRAIL could induce the expression of uPA, IL-8, MMP-7 and MMP-9.and to explore the corresponding potential signaling transduction pathway in pancreatic cancer cells ... TRAIL can stimulate the expression of uPA, IL-8, MMP-7 and MMP-9 in pancreatic cancer cell lines, especially in Colo357wt ... The members of caspases, MEK1/2, PKC, and NF-kappaB are involved in TRAIL induced expression of uPA, IL-8, MMP-7 and MMP-9
Jin et al., Biomed Pharmacother 2013 (Carcinoma, Hepatocellular...) : In addition, c-Jun/AP-1 was rapidly activated upon stimulation with anisomycin ; however, the knockdown of c-Jun/AP-1 expression by c-Jun siRNA markedly reduced anisomycin plus TRAIL induced loss of MMP and apoptosis