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CAPN5 — MMP3

Text-mined interactions from Literome

Morita et al., Biochem Biophys Res Commun 2006 (Arthritis, Rheumatoid) : Mu-calpain is involved in the regulation of TNF-alpha induced matrix metalloproteinase-3 release in a rheumatoid synovial cell line ... These findings suggest that calpain , particularly mu-calpain, regulates MMP-3 release by rheumatic synovial cells, in addition to exerting its own degradative action on cartilage
Li et al., Diabetes 2011 (Cardiomyopathy, Hypertrophic...) : In cultured cardiac fibroblasts, high glucose induced proliferation and MMP activities were prevented by calpain inhibition
Subramanian et al., J Cardiovasc Pharmacol 2012 (Aortic Aneurysm, Abdominal...) : Inhibition of calpain , a calcium activated neutral cysteine protease, by overexpression of its endogenous inhibitor, calpastatin, attenuates AngII induced leukocyte infiltration, perivascular inflammation, and MMP activation in mice
Singh et al., Can J Physiol Pharmacol 2012 (Anoxia...) : On the other hand, inhibition of calpain activity upon treatment with leupeptin or MDL 28170 significantly reduced the MMP activity in addition to attenuating the I/R induced alterations in cardiac function and Na ( + ) /K ( + ) -ATPase activity