Gene interactions and pathways from curated databases and text-mining

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ETS1 — MYLIP

Text-mined interactions from Literome

Itoh et al., J Biol Chem 2010 : In the present study, using microRNA array and in silico analyses, we found that miR-208 is closely involved in preosteoblast differentiation by partially regulating the expression of Ets1 ( V-ets erythroblastosis virus E26 oncogene homolog 1 ), which transactivates osteopontin, runt related transcription factor 2, parathyroid hormone related protein, and type I procollagen
Mattia et al., Pigment Cell Melanoma Res 2011 : Differently from 293FT cells or early stage melanomas, where unphosphorylated ETS-1 represses miR-222 transcription, in metastatic melanoma the constitutively Thr-38 phosphorylated fraction of ETS-1 induces miR-222
Roy et al., Microcirculation 2012 (Anoxia...) : We further demonstrated that hypoxia-sensitive miR-200b is involved in induction of angiogenesis by directly targeting Ets-1 in HMECs
Zheng et al., Mol Cancer Res 2013 (Neoplasm Invasiveness...) : In addition, the effects of miR-145 on Ets1 expression, migration, invasion, and angiogenesis were rescued by restoration of Ets1 expression in these cells
Zheng et al., PloS one 2013 (Neoplasm Invasiveness...) : Ectopic expression or knockdown of miR-9 resulted in responsively altered expression of cyclin D1, Ets1 and their downstream targets phosphorylated retinoblastoma and matrix metalloproteinase 9 in cultured gastric cancer cell lines SGC-7901 and AGS ... Restoration of miR-9 mediated down-regulation of cyclin D1 and Ets1 by transient transfection, rescued the cancer cells from decrease in proliferation, migration and invasion