Gene interactions and pathways from curated databases and text-mining

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NCF4 — PIK3R1

Text-mined interactions from Literome

Ellson et al., EMBO J 2006 : Wortmannin inhibition of the S. aureus oxidase response correlates with inhibition of phagosomal PtdIns3P accumulation and overlaps with the reduction in this response caused by the R58A mutation, suggesting PI3K regulation of this response is substantially dependent on PtdIns3P binding to p40(phox)
Utomo et al., J Immunol 2006 : The FcgammaR mediated oxidative burst defect in Vav-deficient cells was linked to aberrant Rac activation as well as Rac- and actin-polymerization independent, but PI3K dependent , phosphorylation of the NADPH oxidase component p40(phox)