Gene interactions and pathways from curated databases and text-mining

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NFKB1 — P4HB

Text-mined interactions from Literome

Kotani et al., Shock 2003 (Inflammation) : TNFR-1 ( p55 ) and Fas share a death domain which is critical for apoptosis signaling whereas TNFR-p55 and TNFR-2 ( p75 ) can activate NF-kappaB leading to anti-apoptotic proteins expression such as A1
Higuchi et al., Biochem Biophys Res Commun 2004 : Protein disulfide isomerase suppresses the transcriptional activity of NF-kappaB ... We report here that the transcriptional activity of NF-kappaB is negatively regulated by protein disulfide isomerase (PDI)