Gene interactions and pathways from curated databases and text-mining

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NOS1 — PIK3R1

Text-mined interactions from Literome

Kristof et al., J Biol Chem 2003 (Inflammation) : The role of mTOR and PI3K in the activation of human inducible nitric oxide synthase transcription by cytokines and lipopolysaccharide (LPS) was investigated in lung epithelial adenocarcinoma ( A549 ) cells
Liu et al., Circulation 2003 (MAP Kinase Signaling System) : In endothelial cells, aldosterone caused a phosphatidylinositol 3-kinase (PI3K) dependent increase in nitric oxide synthase activity as well as PI3K dependent activation of extracellular signal regulated kinase 1/2 and p70 S6 kinase
Jia et al., J Biol Chem 2004 : VEGF-D induced strong but more transient phosphatidylinositol 3-kinase (PI3K) mediated Akt activation and increased PI3K dependent endothelial nitric-oxide synthase phosphorylation and cell survival more weakly
Sun et al., Toxicol Appl Pharmacol 2006 : Serine 1179 phosphorylation of endothelial nitric oxide synthase caused by 2,4,6-trinitrotoluene through PI3K/Akt signaling in endothelial cells
Yang et al., Exp Physiol 2010 (Hypertension) : These vasorelaxant responses among the three groups became similar after endothelial denudation and pretreatment with the PI3K inhibitor, NOS inhibitor or SOD