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CDKN1A — NOX1

Text-mined interactions from Literome

Katsume et al., Arterioscler Thromb Vasc Biol 2011 (Aortic Diseases...) : Lysophosphatidylcholine activated PYK2 induced NADPH oxidase mediated ROS generation and ROS mediated synthesis of tumor necrosis factor-a (TNFa), vascular cell adhesion molecule-1 ( VCAM-1 ), monocyte chemotactic protein-1 (MCP-1), and p21Cip1/Ets-1
Bromberg et al., J Biol Chem 1994 : The GDP bound form of the small G protein Rac1 p21 is a potent activator of the superoxide forming NADPH oxidase of macrophages ... The GDP bound form of Rac1 p21 complexed to Rho GDI functioned as a potent activator of NADPH oxidase in a cell-free system that contained no free GTP or ATP ... We propose that the GDP bound form of Rac1 p21 might be the physiological activator of NADPH oxidase in macrophages, following its dissociation from Rho GDI, and that nucleotide exchange or conversion to GTP is not necessarily involved
Sawai et al., Biochem Biophys Res Commun 1993 (Leukemia, Promyelocytic, Acute) : Combination of arachidonic acid and guanosine 5'-O- ( 3-thiotriphosphate ) induce translocation of rac p21s to membrane and activation of NADPH oxidase in a cell-free system