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NOX5 — TAT

Text-mined interactions from Literome

Wu et al., J Virol 2004 : We conclude that Tat induces actin cytoskeletal rearrangements through PAK1 and downstream activation of the endothelial NADPH oxidase
Sun et al., Circ Res 2005 (Calcium Signaling...) : The increases in NADPH oxidase activity and ethidium fluorescence were blocked by either the AT(1) receptor antagonist losartan or by the selective NAD ( P ) H oxidase inhibitor gp91ds-tat
Turchan-Cholewo et al., Antioxid Redox Signal 2009 : The present study was undertaken to evaluate the specific effects of Tat on NADPH oxidase in microglia and macrophages, and to determine the specific role of NADPH oxidase in Tat induced cytokine/chemokine release and neurotoxicity ... Together, these data describe a specific and biologically significant signaling component of the macrophage/microglial response to Tat, and suggest the neuropathology associated with HIV infection might originate in part with Tat induced activation of NADPH oxidase
Gupta et al., Neurosci Lett 2010 (Inflammation) : Furthermore, Tat increased expression of the catalytic subunit of x ( c ) ( - ) ( xCT ), but Tat induced increases in xCT mRNA were not affected by inhibition of NADPH oxidase or x ( c ) ( - ) activity
He et al., ASN neuro 2011 : Gp91ds-tat , a specific peptide inhibitor of NADPH oxidase , and Mn ( III ) -tetrakis ( 4-benzoic acid ) -porphyrin chloride, an ROS scavenger, effectively abrogated Aß-induced ROS production
Mukohda et al., J Vet Med Sci 2013 : Gp91ds-tat ( 0.1 µM ), an inhibitor of nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase ( NOX ), prevented the impairment of endothelium dependent relaxation and the decrease in eNOS protein caused by MGO