Gene interactions and pathways from curated databases and text-mining

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NTRK2 — PIK3R1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Li et al., Cell Death Differ 2007 (Neuroblastoma) : Previously, we found BDNF activation of TrkB through PI3K/Akt protects NB from etoposide/cisplatin induced cell death
Jin et al., Cancer Res 2007 (Cell Transformation, Neoplastic) : Here, we define some aspects of the molecular mechanisms regulating ETV6-NTRK dependent Ras-Erk1/2 and PI3K-Akt activation
Yamada et al., J Biol Chem 1997 : These results indicate that the activation of TrkB by BDNF induces the activation of PI3-K via IRS-1 and -2 rather than by a direct interaction of TrkB with PI3-K in cultured cortical neurons