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IL8 — PAF1

Text-mined interactions from Literome

Nasu et al., Mol Hum Reprod 1999 (Endometrial Neoplasms...) : C-PAF stimulated IL-6 and IL-8 transcription in ESC
Arbabi et al., Arch Surg 1999 : Although PAF did not induce significant IL-8 production, it potentiated LPS induced IL-8 production
Countryman et al., J Invest Dermatol 2000 : Pretreatment with PAF receptor antagonists inhibited both carbamoyl-PAF induced and ultraviolet-B induced interleukin-8 production in the PAF-receptor positive cells, but not in control KB cells
Adams et al., J Trauma 2000 (Wounds and Injuries) : Whereas GRO-alpha primed IL-8 and IL-8 primed PAF in normal PMNs, GRO-alpha paradoxically suppressed IL-8 responses and IL-8 suppressed PAF responses in trauma PMNs. PAF priming of IL-8 responses was unaffected by injury
Beaudeux et al., Clin Chim Acta 2004 (Inflammation) : The effects of PAF and oxidised LDL on the production of monocyte chemoattractant protein-1 and interleukin-8 were also examined
Szappanos et al., Naunyn Schmiedebergs Arch Pharmacol 2005 : Finally, up to 2 mug/ml, PAF did not induce the production of pro-inflammatory cytokines such as IL-6, IL-8 , and TNF-alpha
Kushikata et al., Neurosci Lett 2006 (Fever) : PAF and its receptor are found in brain and PAF affects or is affected by the production of sleep promoting cytokines such as interleukin-1
Bussolino et al., J Biol Chem 1992 : IL-8 promotes in a dose dependent fashion ( 1-100 ng/ml ) a rapid synthesis of PAF , which is only partially released
Wirthmueller et al., Biochem Biophys Res Commun 1991 : NAP-1/IL-8 does not induce the synthesis of PAF and LTB4 from endogenous phospholipid precursors, even after preincubation with GM-CSF
Kawano et al., Am J Reprod Immunol 2007 : Our data indicated that IL-8 and GROalpha were regulated by C-PAF
Ogura et al., Auris Nasus Larynx 2008 (Otitis Media with Effusion) : We examined the effect of platelet activating factor (PAF) on IL-8 production in cultured rat middle ear epithelial cells ( RMECs ), and the concentrations of cytokine, PAF, and PAF-acetylhydrolase (PAF-AH) were also examined in the PAF induced experimental OME ( otitis media with effusion ) of rats ... Both PAF and C-PAF, which is a stable analogue of PAF, significantly induced production of IL-8 in the RMECs in a dose dependent manner ... The PAF induced IL-8 production was abolished by co-incubation with WEB2170, a specific PAF receptor antagonist
Wang et al., Mediators Inflamm 1996 : Our previous studies have shown that EsA could reduce the release of platelet activating factor (PAF) from rat macrophages, and inhibit interleukin-1 and interleukin-6 production from routine macrophages
Chang et al., Exp Lung Res 2009 (Inflammation) : SP, bradykinin, protease activated receptor 2 agonist, and platelet activating factor (PAF) stimulated IL-8 production in SAECs, whereas only SP and PAF up-regulated CINC-1 ( a rat IL-8 homolog ) in RLMVECs ... Using signaling inhibitors, the authors investigated PAF induced IL-8 expression and SP-induced CINC-1 expression in primary cells
Sharif et al., Molecular vision 2009 : PAF induced production of IL-6, IL-8 , and GM-CSF from HCECs was also blocked by these PAF antagonists ( IC ( 50 ) =4.6- 8.6 microM )
Borthakur et al., Inflamm Bowel Dis 2010 : siRNA silencing of Bcl10 was used to examine its role in PAF induced NF-kappaB activation and IL-8 production ... Bcl10 was required for PAF induced I kappaB alpha phosphorylation, NF-kappaB activation, and IL-8 production in NCM460, a cell line derived from normal human colon, and Caco-2, a transformed human intestinal cell line
Sharif et al., J Ocul Pharmacol Ther 2010 : However, PAF did not stimulate the generation of IL-6, IL-8 , TNF-alpha, and MMP-1 to any significant level and in a consistent manner
Bussolino et al., Biochim Biophys Acta 1987 : These findings indicate that interleukin 1 induces the PAF synthesis by a deacylation/reacetylation mechanism into human endothelial cells
Au et al., J Immunol 1994 : FMLP, PAF , and a stable PAF agonist did not stimulate significant IL-8 production, however, a calcium ionophore ( A23187 ) did induce IL-8 release and this was suppressed by UK 74505
Roth et al., J Exp Med 1996 : PAF induced transcription of protooncogenes c-fos and c-jun as well as of interleukin (IL)-6 and IL-8 genes in human fibroblasts ... Using signaling inhibitors, we demonstrate that PAF induced transcription of the c-fos, IL-6, and IL-8 genes, as well as proliferation, require activation of pertussis toxin-sensitive G proteins, tyrosine kinases, and protein kinase C ( PKC )