Gene interactions and pathways from curated databases and text-mining

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PARP1 — PIK3CG

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Canobbio et al., Blood 2009 : However, PI3Kbeta, but not PI3Kgamma , enzymatic activity was absolutely required for Akt phosphorylation, Rap1 activation, and platelet aggregation downstream of the immunoreceptor tyrosine based activation motif ( ITAM ) -bearing receptor glycoprotein VI (GPVI)
Gilio et al., J Biol Chem 2009 (Thrombosis) : Furthermore, PI3Kalpha/beta, but not PI3Kgamma , contributed to GPVI induced Rap1b activation and, surprisingly, also to Rap1b independent platelet activation via GPVI