Gene interactions and pathways from curated databases and text-mining

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BAX — PDCD1

Text-mined interactions from Literome

Clark et al., FASEB J 1999 (Craniocerebral Trauma...) : The Bcl-2 family members Bcl-2 and Bcl-xL suppress programmed cell death, whereas Bax promotes programmed cell death
Abudugupur et al., Cell Death Differ 2002 : Thus, the ARL1 gene plays an important role in the formation of central vacuoles and in the progression of programmed cell death induced by cell-cycle arrest or Bax
Alvarez et al., Medicina (B Aires) 2001 (Liver Neoplasms...) : In conclusion, preneoplastic hepatocytes in the IFN alpha-2b treated rats undergo programmed cell death as a result of a significant increase of Bax and its translocation to the mitochondria
Vogel et al., Cerebellum 2002 : The purpose of this review is to summarize recent findings about the role of Bcl-2 and Bax in regulating programmed cell death in the cerebellum during normal development and in a mouse model of cell autonomous and target related cell death, the Lurcher mutant
Gan et al., New Phytol 2009 : The findings that NbLCB ( 2 ) silencing in Nicotiana benthamiana enhanced elicitor triggered HCD, combined with the fact that myriocin, a potent inhibitor of SPT, had no effect on Bax induced programmed cell death , suggested that suppression of cell death was not involved in the dominant negative effect that resulted from BcLCB ( 2 ) overexpression
Gomez et al., Methods Mol Biol 2011 : Bax is an inducer of programmed cell death , and Ku70 is a multifunctional protein maintaining genomic stability and protecting cells from death by inhibiting the cytotoxic activity of Bax
Hara et al., Neurol Res 1997 (Astrocytoma...) : Expression of Bax and bcl-2 proteins, regulators of programmed cell death , in human brain tumors