Gene interactions and pathways from curated databases and text-mining

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PDE3B — PIK3R1

Text-mined interactions from Literome

Ahmad et al., Cell Signal 2000 : We report here that the PI3K inhibitor, wortmannin, prevented the IGF-1 dependent stimulation of PDE3B activity
Ahmad et al., Biochem J 2007 : Another PI3K inhibitor, LY294002, and the tyrosine kinase inhibitor, Genistein, also inhibited insulin induced activation of PDE3B and its co-immunoprecipitation with PKB
Wilson et al., J Biol Chem 2011 : Interestingly, we also show that PDE3B binds directly to p84, a PI3K? regulatory subunit, and that this interaction allows PI3K? recruitment to the PDE3B-EPAC1 complex