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PDGFD — SMC2

Text-mined interactions from Literome

Thomas et al., Am J Physiol Heart Circ Physiol 2009 (Atherosclerosis...) : Here we demonstrate that PDGF-DD inhibited expression of multiple SMC genes, including SM alpha-actin and SM myosin heavy chain, and upregulated expression of the potent SMC differentiation repressor gene Kruppel-like factor-4 at the mRNA and protein levels
Alexander et al., Physiol Genomics 2012 (Inflammation...) : Interestingly, PDGF-DD induced SMC marker gene repression was not NF-?B dependent ... Results demonstrate that IL-1ß- but not PDGF-DD induced phenotypic modulation of SMC is characterized by NF-?B dependent activation of proinflammatory genes, suggesting the existence of a distinct inflammatory SMC phenotype