Gene interactions and pathways from curated databases and text-mining

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PECAM1 — VEGFA

Text-mined interactions from Literome

Mantena et al., Photochem Photobiol 2005 (Skin Neoplasms) : With respect to the tumor vasculature, EGCG decreased the expression of CD31 , a cell surface marker of vascular endothelial cells, and inhibited the expression of vascular endothelial growth factor in tumors, which are essential for angiogenesis
Rajesh et al., Circ Res 2005 : Second, we used D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol ( D-PDMP ), an inhibitor of LacCer synthase and glucosylceramide synthase, that significantly mitigated VEGF induced PECAM-1 expression and angiogenesis ... Also, VEGF/LacCer induced PECAM-1 expression and angiogenesis was mitigated by protein kinase C and phospholipase A2 inhibitors
Lucerna et al., Blood 2007 (Carotid Artery Diseases...) : VEGF-A indeed induced a differential expression of VCAM-1 and PECAM-1 in endothelial cells