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PGP — PIK3R1
Text-mined interactions from Literome
Liang et al., FEBS J 2009
(Stomach Neoplasms) :
Inhibition of
PI3K/Akt by LY2940002 or Akt siRNA
leads to inhibition of PrP ( C ) -induced drug resistance and
P-gp upregulation in gastric cancer cells, indicating a possible novel mechanism by which PrP ( C ) regulates gastric cancer cell survival
Liu et al., Oncol Rep 2010
(Breast Neoplasms) :
LY294002, specific inhibitor of
PI3K could
suppress survivin and
P-gp expression, decreased survivin promoter activity and enhanced cell sensitivity to drugs