Gene interactions and pathways from curated databases and text-mining

◀ Back to PLCG2

PIK3CA — PLCG2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Bobe et al., Blood 2001 (Agammaglobulinemia) : Phosphatidylinositol 3-kinase dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation
Yamamori et al., Biochem Biophys Res Commun 2004 : Furthermore, PI3K inhibitors reduced the activation of phospholipase Cgamma2 without affecting tyrosine phosphorylation on it
Dai et al., Mol Cell Biol 2006 : Interestingly, PLCgamma2 deficiency had no effect on BCR mediated PI3K activation, whereas PI3K deficiency only partially blocked activation of PLCgamma2
Gilio et al., J Biol Chem 2009 (Thrombosis) : The targeting of platelet PI3Kalpha or -beta strongly and selectively suppressed GPVI induced Ca ( 2+ ) mobilization and inositol 1,4,5-triphosphate production, thus demonstrating enhancement of phospholipase Cgamma2 by PI3Kalpha/beta