Gene interactions and pathways from curated databases and text-mining

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PIK3CG — PIK3R1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: PIK3R1 — PIK3CG (interaction, mapped from grid bind reactome kegg_pathways)
  • STRING interaction: PIK3CG — PIK3R1 (interaction, mapped from grid bind reactome kegg_pathways)

Text-mined interactions from Literome

Webb et al., J Immunol 2005 : This work demonstrates that PI3K activity is critical for T cell development and depends on the combined function of p110gamma and p110delta
Zhang et al., International journal of clinical and experimental medicine 2009 : The inhibitors of protein tyrosine kinases and PI3K , genistein and PI3Kgamma inhibitor II, were used to elucidate the role of protein tyrosine kinase and PI3K in hypoxic modulation of preproET-1 expression
Janas et al., J Exp Med 2010 : Here, we show that PI3K signaling from the preTCR requires p110delta, but not p110gamma