Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — PLA2G1B

Text-mined interactions from Literome

Park et al., J Immunol 2003 : Pretreatment with LY294002, a PI3K inhibitor, strongly suppressed group IIA PLA(2) induced iNOS expression and PI3K/Akt activation
Myou et al., J Immunol 2003 (MAP Kinase Signaling System) : We find that PI3K is required for gIV-PLA(2) activation and hydrolytic production of AA in activated eosinophils ... Our data suggest that this essential PI3K independently activates gIV-PLA(2) through a pathway that does not involve MAPK
Araki et al., Free Radic Biol Med 2005 : PLA2 , COX, PKC, NADH dehydrogenase, and XO inhibitors prevented the CA-induced ROS generation but not ERK 1/2, PI 3 K , p38 MAPK, and MLCK inhibitors
Wang et al., Cardiovasc Res 2010 (Atherosclerosis) : Inhibition of either PI3K or p38 MAPK completely blocked oxLDL induced lp-PLA2 expression