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FGF4 — PLCG1

Pathways - manually collected, often from reviews:

• Reactome Reaction: FGF4 → PLCG1 (reaction) Carpenter et al., Exp Cell Res 1999, Cross et al., J Cell Sci 2000, Hart et al., Oncogene 2000, Chen et al., Oncogene 2005, Hatch et al., J Biol Chem 2006, Cha et al., Mol Cancer Res 2008, Gartside et al., Mol Cancer Res 2009, di Martino et al., Oncogene 2009
• Reactome Reaction: FGF4 → PLCG1 (indirect_complex) Carpenter et al., Exp Cell Res 1999, Cross et al., J Cell Sci 2000, Hart et al., Oncogene 2000, Chen et al., Oncogene 2005, Hatch et al., J Biol Chem 2006, Cha et al., Mol Cancer Res 2008, Gartside et al., Mol Cancer Res 2009, di Martino et al., Oncogene 2009

Text-mined interactions from Literome

Sa et al., Mol Cell Biochem 1999 : Upon binding to FGFR1, basic FGF stimulates cytosolic form of phospholipase A2 ( cPLA2 ), phospholipase C-gamma1 ( PLC-gamma1 ) and phospholipase D ( PLD ), the key enzymes for the production of various lipid second messengers, in a tyrosine kinase dependent manner ... Upon binding to FGFR1, basic FGF stimulates cytosolic form of phospholipase A2 ( cPLA2 ), phospholipase C-gamma1 ( PLC-gamma1 ) and phospholipase D ( PLD ), the key enzymes for the production of various lipid second messengers, in a tyrosine kinase dependent manner
Koyama et al., Dev Growth Differ 2008 : However, FGF7 and FGF10 stimulated phosphorylation of both PLCgamma1 and PI3K, but elicited only minimal phosphorylation of ERK-1/2