Gene interactions and pathways from curated databases and text-mining

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MAPK6 — PLCG2

Text-mined interactions from Literome

Kornmann et al., Gastroenterology 2002 (Cell Transformation, Neoplastic...) : In vitro, TAKA-1 cells stably transfected with FGFR-1 IIIc exhibited increased basal growth ; enhanced basal tyrosine phosphorylation of FGFR substrate-2 (FRS2), Shc, and phospholipase Cgamma ; and increased activation of mitogen activated protein kinase ( MAPK )
Chen et al., J Biol Chem 2002 : Incubation of cells with the specific EGFR inhibitor AG4178 blocked MbetaCD induced phosphorylation of EGFR, SHC, phospholipase C-gamma , and Gab-1 as well as MAPK activation
Zheng et al., J Neurochem 2008 (Ion Channel Gating) : Although previous studies suggested the roles of mitogen activated protein kinase , phospholipase C-gamma mediated intracellular calcium ( [ Ca2+ ] i ) increase , and extracellular calcium influx in regulating Akt activation, the cellular mechanisms are largely unknown
Rho et al., J Pharmacol Exp Ther 1997 : Involvement of phospholipase C-gamma2 in activation of mitogen activated protein kinase and phospholipase A2 by zooxanthellatoxin-A in rabbit platelets ... These results suggest that ZT-A stimulates a protein tyrosine kinase in the presence of external Ca++, resulting in the activation of MAPK probably via PLC-gamma2 and protein kinase C