Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — PLCG2

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Bobe et al., Blood 2001 (Agammaglobulinemia) : Phosphatidylinositol 3-kinase dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation
Yamamori et al., Biochem Biophys Res Commun 2004 : Furthermore, PI3K inhibitors reduced the activation of phospholipase Cgamma2 without affecting tyrosine phosphorylation on it
Dai et al., Mol Cell Biol 2006 : Interestingly, PLCgamma2 deficiency had no effect on BCR mediated PI3K activation, whereas PI3K deficiency only partially blocked activation of PLCgamma2
Peruzzi et al., J Immunol 2007 (Calcium Signaling) : We found that CIN85 overexpression inhibits the FcepsilonRI induced tyrosine phosphorylation of phospholipase Cgamma , thus altering calcium mobilization