Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — PPP1R3A

Text-mined interactions from Literome

Leung et al., FEBS Lett 2006 : Rg1 increased the phosphorylation of GR, phosphatidylinositol-3 kinase (PI3K) , Akt/PKB and endothelial nitric oxide synthase (eNOS) leading to increase nitric oxide ( NO ) production in human umbilical vein endothelial cell
Leung et al., J Biol Chem 2006 : In addition, the GR antagonist RU486 was able to inhibit Rg1 induced PI3K/Akt and beta-catenin activation
Yin et al., J Mol Med (Berl) 2011 (Disease Models, Animal...) : Rg1 induced activation of PI3K/Akt also contributed to the downregulation of p38 MAPK