Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — PREX1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Barber et al., J Biol Chem 2007 : Activation of PI3K alone is not sufficient to promote significant membrane translocation of P-Rex1 ... Co-expression of P-Rex1 with either Gbetagamma or PI3K caused only an insignificant increase in P-Rex1 membrane localization, whereas Gbetagamma and PI3K together synergistically caused a robust increase in membrane localized P-Rex1 to 23 % of the total
Wertheimer et al., Cell Signal 2012 (Breast Neoplasms...) : P-Rex1 is activated by the PI3K product PIP3 and Gß? subunits, and integrates signals from ErbB receptors and GPCRs