◀ Back to FOXO4

FOXO4 — PRKAA1

Text-mined interactions from Literome

Greer et al., Curr Biol 2007 : Lastly, we find that AMPK activates FOXO/DAF-16 dependent transcription and phosphorylates FOXO/DAF-16 at previously unidentified sites, suggesting a possible direct mechanism of regulation of FOXO/DAF-16 by AMPK
Nystrom et al., International journal of clinical and experimental medicine 2008 : Our data indicate FoxO mRNA expression is down-regulated by AMPK activation and energy depletion in cultured myotubes, but that a contrasting increase in FoxO1 and FoxO3 mRNA is observed in vivo with the agent ( and in response to sepsis ) suggesting the expression of these FoxOs may be controlled by other hormonal or energy sensing cues under in vivo conditions
Greer et al., Ann N Y Acad Sci 2009 : AMPK phosphorylation enhances FoxO transcriptional activity, leading to the expression of specific target genes involved in stress resistance and changes in energy metabolism
Vadlakonda et al., Frontiers in oncology 2013 : Depletion of energy leads to inactivation of mTORC1, activation of AMPK , FoxO , and promotes constitution of mTORC2 that leads to phosphorylation of Akt S473