Gene interactions and pathways from curated databases and text-mining

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CRH — PRKAR2B

Text-mined interactions from Literome

Yamamori et al., J Mol Endocrinol 2004 (Calcium Signaling) : Altogether, we conclude that not only the cAMP/PKA but also the calcium/CaMKIV signaling pathway is involved in the regulation of CRH gene expression ... Furthermore, CREB is thought to be involved in CaMK- as well as cAMP/PKA mediated CRH gene expression
Agarwal et al., Brain Res Mol Brain Res 2005 : Pituitary adenylate cyclase activating polypeptide ( PACAP ) mimics neuroendocrine and behavioral manifestations of stress : Evidence for PKA mediated expression of the corticotropin releasing hormone (CRH) gene
Nanmoku et al., Neurosci Lett 2005 (Second Messenger Systems) : Furthermore, urocortin induced changes in TH-mRNA and activity were inhibited by H89 ( a PKA inhibitor ) and SQ22536 as well as alpha-helical CRF- ( 9-41 )
Hu et al., J Endocrinol 1992 (Second Messenger Systems) : These data provide direct evidence for a role for both PKC- and PKA mediated mechanisms in the regulation of CRF , AVP and oxytocin release and for differential effects of both glucocorticoids and mineralocorticoids on PKA- and PKC stimulated responses
Uh et al., Reproductive biology and endocrinology : RB&E 2009 : Classically protein kinase A (PKA) and transcription factor activator protein 1 (AP-1) mediate the cyclic AMP ( cAMP ) induced-corticotrophin releasing hormone (CRH) expression in the placenta
Yang et al., Br J Pharmacol 2011 (Arrhythmias, Cardiac) : Urocortin 2 enhanced contractility in mouse ventricular myocytes via activation of CRF2 receptors in a cAMP/PKA- and Ca² ( + ) /CaMKII dependent manner
Ji et al., Molecular pain 2013 (Pain...) : CRF increased a latent NMDA receptor mediated EPSC, and this effect also required CRF1 and PKA but not CRF2 and PKC
Gwosdow et al., Am J Physiol 1994 : In contrast, CRF stimulated PKA activity and ACTH secretion were inhibited by 2'5'-DDA ... Inhibition of PKA with the PKA inhibitor, H-8, blocked activation of PKA and ACTH secretion by both IL-1 alpha and CRF in AtT-20 cells