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IL1B — PRKCA

Text-mined interactions from Literome

Chen et al., Mol Pharmacol 2000 : Taken together, IL-1beta activates phosphatidylcholine-specific phospholipase C and induces activation of PKCalpha and protein tyrosine kinase, resulting in the stimulation of NIK, IKK2, and NF-kappaB in the ICAM-1 promoter, then initiation of ICAM-1 expression
Radeff et al., Exp Cell Res 2001 (Bone Resorption) : PTH, tumor necrosis factor-alpha (TNF-alpha), and interleukin-1 beta (IL-1 beta) induced translocation of PKC-alpha and -beta ( I ) to the plasma membrane in UMR-106 cells within 5 min ... In contrast, LY379196 did not affect PTH, TNF-alpha-, or IL-1 beta stimulated translocation of PKC-alpha
Ginnan et al., Am J Physiol Cell Physiol 2006 : Stimulation with IL-1beta activated PKC-alpha and -delta, which was blocked using the PLC inhibitor U-73122
Dasu et al., Am J Physiol Endocrinol Metab 2007 (MAP Kinase Signaling System) : Data from inhibitor and small interfering RNA experiments indicate that IL-1beta release under HG is mediated by PKC-alpha , via phosphorylation of p38 MAPK, and ERK1/2 leading to NF-kappaB activation, resulting in increased mRNA and protein for IL-1beta