Gene interactions and pathways from curated databases and text-mining

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MDM2 — PRR5

Text-mined interactions from Literome

Mytar et al., Inflamm Res 2004 : This study addressed the role of the pattern recognition receptors ( PRR ) , which recognize different molecular structures present on microorganisms, apoptotic, senescent and tumor cells, in the stimulation of human monocyte and monocyte derived macrophages ( MDM ) for the production of intracellular cytokines
Lyo et al., Biochem Biophys Res Commun 2010 (Kidney Neoplasms) : We report here that the PLD/mTOR dependent stabilization of HDM2 involves mTORC2 and the AGC family kinase serum- and glucocorticoid-inducible kinase 1 ( SGK1 )