Gene interactions and pathways from curated databases and text-mining

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PTH — TGFB2

Text-mined interactions from Literome

Sanders et al., Endocrinology 2000 (Bone Neoplasms...) : Secretion of PTH related peptide (PTHrP) from breast cancer cells is thought to play a key role in osteolytic metastases and is increased by transforming growth factor-beta ( TGFbeta ), which is released from resorbed bone
Seitz et al., J Bone Miner Res 1992 (Osteosarcoma) : Effect of transforming growth factor beta on parathyroid hormone receptor binding and cAMP formation in rat osteosarcoma cells
Sowa et al., Cancer Res 2004 (Hyperparathyroidism, Secondary...) : Here we have investigated the roles of transforming growth factor ( TGF ) -beta and menin, the product of the multiple endocrine neoplasia type 1 ( Men1 ) gene, in the proliferation and PTH production of parathyroid cells from either patients with secondary hyperparathyroidism or Men1
Naito et al., Endocrine 2006 (Hypercalcemia...) : The proband 's cultured parathyroid cells lacked the normal reduction in proliferation and parathyroid hormone secretion in response to transforming growth factor- beta
Qiu et al., Nat Cell Biol 2010 : Here we show that transforming growth factor ( TGF)-beta type II receptor (TbetaRII ) forms an endocytic complex with PTH1R in response to PTH and regulates signalling by PTH and TGF-beta