Gene interactions and pathways from curated databases and text-mining

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ADCY7 — PTHLH

Text-mined interactions from Literome

Hömme et al., Endocrinology 2003 (Osteosarcoma) : The PTH/PTHrP receptor stimulates both adenylate cyclase- and phospholipase C-dependent signaling pathways via different G proteins
Trizna et al., Pharmacology 1991 : In proximal convoluted tubules PTH and PTHrP stimulated adenylate cyclase to the same extent and with similar potencies
Azarani et al., J Biol Chem 1995 : Human PTH- ( 1-34 ) and PTHRP- ( 1-34 ) stimulated adenylate cyclase and PKC activity, whereas the PTH analogues, PTH- ( 3-34 ), PTH- ( 28-42 ), and PTH- ( 28-48 ), selectively enhanced only PKC activity
Suda et al., J Cell Physiol 1996 (Osteosarcoma) : Examination of the populations obtained from newborn rat calvariae by sequential collagenase digestion revealed that the early digests exhibited low ALP activity, low expression of PTH/PTHrP receptor mRNA, and no adenylate cyclase response to PTHrP ( 1-34 )
Azarani et al., J Biol Chem 1996 : Both PTH- ( 1-34 ) and PTHRP- ( 1-34 ) stimulated adenylate cyclase and PKC activities in these cells, whereas PTH- ( 3-34 ), PTH- ( 28-42 ), and PTH- ( 28-48 ) selectively enhanced only PKC activity