◀ Back to PIK3R1
PIK3R1 — PTK2
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
PIK3R1
—
PTK2
(direct interaction, far western blotting)
Guinebault et al., J Cell Biol 1995*
-
IRef Biogrid Interaction:
PIK3R1
—
PTK2
(physical association, affinity chromatography technology)
Guinebault et al., J Cell Biol 1995*
-
IRef Hprd Interaction:
PTK2
—
PIK3R1
(in vivo)
Sieg et al., Nat Cell Biol 2000*, Guinebault et al., J Cell Biol 1995*, Hildebrand et al., Mol Cell Biol 1996*
-
IRef Ophid Interaction:
PTK2
—
PIK3R1
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
IRef Ophid Interaction:
PTK2
—
PIK3R1
(aggregation, confirmational text mining)
Sieg et al., Nat Cell Biol 2000*
Text-mined interactions from Literome
Ling et al., J Cell Biochem 1999
(Astrocytoma) :
Our data suggest a
role for PI3-K and
p125FAK complex formation in
PI3-K activation
Li et al., American journal of physiology. Renal physiology 2006
:
We conclude that
PI3K is involved in mediating the effect of low K intake on ROMK channel activity in the CCD and that the effect of PI3K on SK channels
requires the involvement of
PTK and the cytoskeleton
Hehlgans et al., Int J Radiat Biol 2007
:
On the basis of the presented data, a precise correlation of adhesion-, serum- and
PI3K mediated changes in PI3K/AKT and
FAK/Paxillin/p130Cas signaling cascades was not found
Weidenaar et al., Mol Cancer Res 2013
(Leukemia, Myeloid, Acute...) :
Proteome profiler array analysis of downstream kinases revealed that
PTK/ZK reduced activation of
PI3K/Akt kinase signaling
Lu et al., Eur J Immunol 1996
(Leukemia) :
CD28 induced tyrosine phosphorylation and
PI3-K activation was
independent of p56lck
protein tyrosine kinase ( PTK ) activity ( previously reported to be associated with CD28 ) and was insensitive to inhibition by the PTK inhibitor herbimycin A
Geltz et al., Blood 1998
:
The
protein tyrosine kinase inhibitor, erbstatin analog, partially inhibited p85 and p110 phosphorylation but did not appear to
affect PI3K lipid kinase activity